Revision 1
March 19, 1998
by Radiation, Science, and Health, Inc.,
Edited by J. Muckerheide

1.4
Biology, Genetics & Cancer Research

Figure 1 Figure 2 Figure 3 Figure 4 Figure 5

"The effects of low dose (0.05-1.0 Gy) of total body irradiation (TBI) on non-tumor bearing and tumor bearing mice were investigated. Mice received TBI of 0.1 Gy during 6-12 hours before tumor cell inoculation demonstrated to need larger number of tumor cells (approximately 2.5 times) for 50 per cent tumor incidence, compared to recipient mice not to receive TBI. On the other hand, in tumor bearing mice given 0.1 Gy of TBI, only tumor cell killing effect was not detected, however enhancement of tumor cell killing effect and prolonged growth delay were observed when tumor bearing mice were treated with 0.1 Gy of TBI in combined with local irradiation on tumors, especially cell killing effect was remarkable in dose range over 6 Gy of local exposure. The mechanism of the effect of 0.1 Gy TBI is considered to be host mediated reactions from the other of our experimental results."

[Table 1, Table 2, Table 3, Table 4]

[Editor’s Note: The following tables and figures from Miyamoto and Sakamoto 1987 document their biopositive and anti tumor effects of low-dose radiation. These results have been confirmed, by their later work and others. Note also: these results have been applied to successfully treat cancer in humans in the decade since these results were published. See Section 1.7. Note also: the committed radiation protection bias and control of radiation science policy has constrained research to confirm and apply these results, potentially affecting millions of persons with cancer that may have lived with the success of these low-dose radiation therapies. See also the following 1987 summary by Sakamoto and Miyamoto.]