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"Low Level
Radiation Health Effects: Compiling  the Data"

Revision 1
March 19, 1998

by Radiation, Science, and Health, Inc.
,
Edited by J. Muckerheide

1.9
Conclusions

 

Dr. Dr. Sadao Hattori, Vice President and Director of Research at CRIEPI, states (1997) that:

"In a review article entitled ‘Physical Benefits from Low Levels of Ionizing Radiation’, published in Health Physics in December of 1982, Professor T.D. Luckey of the University of Missouri, asserted the ‘radiation hormesis’ with 200 references.

"This resulted in the first International Symposium on Radiation Hormesis in Oakland, California (August 1985). CRIEPI consulted many specialists about Luckey's paper and studied many other papers such as Lorenz, 1954; Luckey 1980, Liu et al. 1985.

"Radiation hormesis research in Japan has been based on the rationale that if Luckey's claim were to be true, radiation management in Japan has been extremely erroneous.

"CRIEPI organized a Hormesis Research Steering Committee composed of leading specialists in the field concerned, and began research in cooperation with a number of universities, as well as the National Cancer Research Institute, and the National Institute of Radiological Sciences. After obtaining interesting results in various experiments on the health effects of exposure to low doses of radiation, we have proceeded on an expanded program, which involves fourteen universities and two research institutes throughout Japan.

"The interesting results we obtained can be categorized in five groups:

"1. Enhancement of immune systems such as lymphocytes and suppression of cancer,

"2. Radio-adaptive response relating to the activation of DNA repair and apoptosis,

"3. Rejuvenation of cells such as increases of SOD and cell membrane permeability,

"4. Radiation effect on neuro-transmitting system through increase of key enzymes,

"5. Others, including the therapy of adult-disease such as diabetes and hypertension."

"We are now carrying out experimental activities on the effects of low-dose radiation on mammals. After several years of research activities, we are recognizing Luckey's claim. Some basic surveys including Hiroshima, Nagasaki and animal experiments in Japan have brought us valuable information on the health effects of low-dose radiation.

"Formation of ions, free electrons and free radicals by ionizing radiation enhances and creates many comprehensive bio-chemical reactions, followed by significant biological responses.

"Animal tests results give us a certain scientific synopsis on the adaptive response to low dose effect on carcinogenesis and malignant tumor, suppression of cell aging, and activation of biological defense mechanisms.

"We have such an impression that a certain low dose radiation raises some vitalizations of basic biological functions. The recent progress of analytical technique on the observation of DNA structural responses greatly contributes the unbelievable success of our research on the adaptive responses of low dose radiation.

"Analysis of the history of the evolution of living materials through a billion of years shows us all kinds of environmental conditions were put in the extremity of positive utilization without exception in our physical processes, air, water, sun light, temperature, salt, and radiation. This pursuit of the extremity of the positive utilization of the all kinds of environmental factor through the process of evolution is the life itself, in a sense. It is obvious the natural radiation back ground on the earth was fairly higher than present situation in the past days.

"On this sense, the adaptive response is the fundamental characteristics of lives. All kinds of damages caused by environmental influence, diseases, loss of power are to be overcome by enhancement of DNA repair and apoptosis activities. This is the way of adaptive response."
 

     


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