Revision 1
March 19, 1998
by Radiation, Science, and Health, Inc.,
Edited by J. Muckerheide

1.9
Conclusions

"In 1982, Prof. T. D. Luckey asserted ‘Radiation Hormesis’ in the Health Physics Journal. He also published two books. He clearly explained his assertion in his second book, ‘Radiation Hormesis’ (CRC Press 1991) showing bio-positive effects of low level radiation, 10 cGy/y as optimum, 1 Gy/y as acceptable, 10 Gy/y as Maximal Limit to avoid hazardous effect. CRIEPI began our research program to find the scientific truth because his assertion was extremely different from the concept of radiation protection. CRIEPI is now promoting this research with fourteen universities in Japan.

"The interesting results we have obtained can be categorized in five groups.

"1. Enhancement of immune systems such as lymphocytes

and suppression of cancer, etc.,

"2. Radio-adaptive response relating to the activation of

DNA repair and apoptosis,

"3. Rejuvenation of cells such as increase of SOD and cell

membrane permeability,

"4. Radiation effect on neuro-transmitting system through

increase of key enzymes,

"5. Others, including the therapy of adult-disease such as

diabetes and hypertension."

"Evidence that low-level radiation substantially enhances the effectiveness of repair mechanisms is summarized. This finding destroys the theoretical basis (there is no other basis) for use of a linear-no threshold dose-response relationship to estimate the cancer risk of exposure to low-level radiation. Such a methodology will exaggerate the risk. This conclusion is further supported by epidemiological evidence and by studies of the effects of radon exposure in the home, which are reviewed."

"We are now carrying out experimental activities on the effects of low-dose radiation on mammals. After several years of research activities, we are recognizing Luckey’s claim. Some basic surveys including Hiroshima-Nagasaki survivors and animal experiments in Japan have brought us exciting information on the health effects of low-dose radiation."

"Formation of ions, free electrons, and free radicals by ionizing radiation enhances and creates many comprehensive bio-chemical reactions, followed by significant biological responses.

"Animal test results give us a certain scientific synopsis on the radiation hormesis. Some suppression effect on carcinogenesis and malignant tumors. Suppression of cell aging. Activation of biological defense mechanisms.

"We have such an impression that a certain low dose radiation raises some vitalizations of basic biological functions. The recent progress of analytical technique on the observation of DNA structural responses greatly contributes the enormous success of our research on hormesis.

"Our research activities on the biological effects of low-dose radiation are getting to a very exciting stage.

"It seems to me that in the next century we are going to open research to its greatest scope on the mechanism of life."