Radiation, Science, and Health

Author Index to Papers and Documents

Lugwig Feinendegen, M.D.

Science Papers
Technical Articles
Conference Papers
Presentations

Technical Articles
Biologic Responses to Low Doses of Ionizing Radiation: Detriment Versus Hormesis
Part 1. Dose Responses of Cells and Tissues, July 2001, Ludwig Feinendegen, MD, and Myron Pollycove, MD [PDF, 746 KB]
Part 2. Dose Responses of Organisms, September 2001, by Myron Pollycove, MD, and Ludwig Feinendegen, MD [PDF, 455 KB]
Journal of Nuclear Medicine In this two-part special contribution to Newsline, Ludwig Feinendegen and Myron Pollycove present current basic research data supporting radiation hormesis. Both authors believe that such data is often ignored in the face of a persistent and enduring scientific adherence to the linear no-threshold dose presumption. The authors suggest that a reassessment of this data is overdue and could have striking implications for the future practice of nuclear medicine.

Conference Papers
Cellular and Organism Dose-Response: Biopositive (Health Benefit) Effects, Myron Pollycove, M.D., U.S. Nuclear Regulatory Commission, Rockville MD, mxp@nrc.gov; Prof. Emeritus, UC San Francisco; and Ludwig E. Feinendegen, M.D., Prof. Emeritus Julich, and Senior Researcher U.S. DOE and National Institutes of Health, feinendegen@gmx.net
     "Abstract: The genes in every cell continuously undergo an immense amount of metabolic damage by reactive oxygen species (ROS) which is prevented, repaired, and removed by a complex antimutagenic system. Recent studies document low dose radiation stimulation of many cellular functions, including antioxidant prevention, enzymatic repair, and immunologic and apoptotic removal of DNA damage. This homeostatic system is stimulated by a ten, or even a hundredfold increase in background radiation. Enhanced prevention of gene mutations by the spatial and temporal differences of ionizing radiation ROS and metabolic ROS is associated with radiation hormesis: decreased mortality and decreased cancer mortality observed in populations exposed to low dose radiation. Therapeutic stimulation of the immune system by low dose body irradiation prevents and removes cancer metastases in mice, rats, and humans.

Presentations